Postdoctoral Position in Mapping Big Data Systems

2018/06/21   |   academic

Applications are invited for a Postdoctoral fellowship at the University of Barcelona to work with Prof. M. Ángeles Serrano and Prof. Marián Boguñá at the Department of Condensed Matter Physics and UB Institute of Complex Systems (UBICS). The position is funded by a Fundación BBVA grant.

A renormalization group for the multiscale unfolding of complex networks

2018/03/20   |   academic

Maps of complex networks in hyperbolic space are not only attractive visual representations but they are full of meaning and allow us to find out information on the systems and to navigate through them. We can increase the system navigability if we take into account the information provided by the renormalization group, which allows us to unfold networks at the different structural scales that build them up, and which, in addition, turn out to be self-similar, that is, they have the same organization at different scales. These results can also be applied to make reduced versions of the original networks at smaller scales and which have the same properties. The possibility of having reduced copies has a great potential; for instance, they can serve as testbeds to assess expensive processes in original networks, such as new Internet routing protocols.

Synthetic lethality clusters in metabolic networks

2018/01/26   |   academic

Synthetic lethality, in which the combined knockout of two nonessential genes or reactions is lethal, has direct applications in recognising targets for therapeutic treatment of complex diseases and for fighting against undesired resistance. We propose a change of paradigm based on the fact that SL interactions in metabolism are not independent of each other but form complex backup systems, called SL clusters.

latest publications

Multiscale unfolding of real networks by geometric renormalization

Guillermo García-Pérez, Marián Boguñá and M. Ángeles Serrano
Nature Physics doi:10.1038/s41567-018-0072-5 (2018)
theory of complex networks  |  metric spaces

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Metabolic plasticity in synthetic lethal mutants: viability at higher cost

Francesco Alessandro Massucci, Francesc Sagu├ęs, M. ├üngeles Serrano
PLOS Computational Biology 14 e1005949 (2018)
systems biology  |  metabolism

Navigability of temporal networks in hyperbolic space

Elisenda Ortiz, Michele Starnini, M. Ángeles Serrano
Scientific Reports 7 15054 (2017)
theory of complex networks  |  metric spaces